Coronavirus 2019-2020 thread (no unsubstantiated rumours!)

tresriogrande

New Member
Registered Member
Very good point. I will add though that the efficacy rate of the Pfizer/BioNTech vaccine is better than the Chinese vaccines (due to utilising better and modern technology).

This is not true. No evidence to support your conclusion. None of the vaccines were done together in phase III trials , so their efficacy rates are not comparable to each other.


I will note though, that efficacy is not the only statistic by which a vaccine is rated as better or worse than another vaccine.



Agreed. The AP1000 should have been only used for getting experience and technology. After that China should have abandoned it and went 100% for domestic technology and IP.

Ideally these kind of decisions should be taken like these:

For example you would rate the AP1000 best for pure profit reasons, and for the least risk (already developed).

Then you would include criteria such as domestic production(IP, tech etc), national security etc.

And then the different ministries and agencies would conclude what is more important and choose how high each critiria should be categorized.


E.g you could say that National Security is A+, Domestic IP A, Commercial B- etc.

Thats how contracts and decisions should be taken.
 

Tam

Brigadier
Registered Member
I don't think the world is going to return to normal anytime soon, with the mRNA fiasco and the mutants coming out of India... the world will be in some form of COVID induced lockdown (aka artificial demand destruction) for the next five years... or much more

What would be most ironic, is if in the haste to pump out the untested and unproven mRNA vacs in such a rush, later it was determined there is a critical flaw in these experiments that fatally terminated a large percentage of the participants long term... this might conceivably lead to the downfall of Western civilization itself and a large portion of population extinction thereof... all because of their greed and politics and blind hatred of China....

Since this is basically a DNA altering nano drug, imagine if later it was found that one of the long term effects of this mRNA vacs was that the person's children are unable to have children... then in three generations entire Western civilization would be wiped out from the face of the earth and they would have no one to blame but their own selfs


To be clear, mRNA vaccines don't alter DNA. First, because it is what the name says, its RNA. Second, the RNA and nanolipid vehicle has a very short life outside of extremely cold temperatures. They won't last a minute or two in the human body. They are only there to deliver the spike protein. The spike protein itself doesn't alter DNA, they are only there for the memory T-cells to commit to their memory. Even on a live virus, the spike protein doesn't modify DNA, they stay outside of it and is used to poke the cell membrane. Remember that SARS COV-2 happens to be an RNA virus, not a DNA virus.

You have more potential risk of DNA modification with flu or adenovector vaccines, because adenovirus, which is your flu or cold virus, is a DNA virus, but for vaccine purposes, they are dead.

You have more risk of DNA modification getting a common cold than with covid 19 much less with RNA based vaccines.
 

vincent

Grumpy Old Man
Staff member
Moderator - World Affairs
To be clear, mRNA vaccines don't alter DNA. First, because it is what the name says, its RNA. Second, the RNA and nanolipid vehicle has a very short life outside of extremely cold temperatures. They won't last a minute or two in the human body. They are only there to deliver the spike protein. The spike protein itself doesn't alter DNA, they are only there for the memory T-cells to commit to their memory. Even on a live virus, the spike protein doesn't modify DNA, they stay outside of it and is used to poke the cell membrane. Remember that SARS COV-2 happens to be an RNA virus, not a DNA virus.

You have more potential risk of DNA modification with flu or adenovector vaccines, because adenovirus, which is your flu or cold virus, is a DNA virus, but for vaccine purposes, they are dead.

You have more risk of DNA modification getting a common cold than with covid 19 much less with RNA based vaccines.
What is the defect rate in the mRNA process? When millions of strands are produced for each shot, there bound to have some with defective sequences. They may produce proteins that have unknown consequences. The defective mRNA may also do some weird things inside your stem cell which may lead to higher chance of cancers or autoimmune diseases later in life.
 

hashtagpls

Senior Member
Registered Member
What is the defect rate in the mRNA process? When millions of strands are produced for each shot, there bound to have some with defective sequences. They may produce proteins that have unknown consequences. The defective mRNA may also do some weird things inside your stem cell which may lead to higher chance of cancers or autoimmune diseases later in life.
That's what worries me about mRNA vaccines which are cutting edge and new; what are the risks of prion disease after use of mRNA vaccines?
And the thing with prion diseases are they take years and decades before they manifest.
 

Tam

Brigadier
Registered Member
That's what worries me about mRNA vaccines which are cutting edge and new; what are the risks of prion disease after use of mRNA vaccines?
And the thing with prion diseases are they take years and decades before they manifest.

They were being tested before, and for some years, as potential vaccines against ebola and zika. So they are not exactly that new.

Another new technology, recombinant protein, was also being developed for ebola, and that's the basis for the Novavax vaccine for covid. Sinopharm also submitted applications for trials on a third covid vaccine, this time using recombinant protein. I don't know what's the second Sinopharm vaccine.
 

Tam

Brigadier
Registered Member
What is the defect rate in the mRNA process? When millions of strands are produced for each shot, there bound to have some with defective sequences. They may produce proteins that have unknown consequences. The defective mRNA may also do some weird things inside your stem cell which may lead to higher chance of cancers or autoimmune diseases later in life.

Your body has dead strands of proteins all the time from dead cells. Your kidneys filter them out all the time.
 

voyager1

Captain
Registered Member
Lmao these people that think mRNA technology just appeared out of the blue, last year.

I am waiting to see how they react when China starts administrating its own mRNA vaccine.

Facts. mRNA vaccines are the future. Major R&D is happening to start producing new vaccines for diseases
 

vincent

Grumpy Old Man
Staff member
Moderator - World Affairs
They were being tested before, and for some years, as potential vaccines against ebola and zika. So they are not exactly that new.

Another new technology, recombinant protein, was also being developed for ebola, and that's the basis for the Novavax vaccine for covid. Sinopharm also submitted applications for trials on a third covid vaccine, this time using recombinant protein. I don't know what's the second Sinopharm vaccine.
mRNA vaccines have never been introduced to mass market before nor have they been mass produced before. Does anyone know the production defect rate? Does even Pfizer or Moderna know? What kinds of defects? What effects those defective sequences have? Is anyone doing a long-term study on potential effects of the mRNA vaccines? Since mRNA vaccines and Adeno vector vaccines follow the same working principle and Americans are all pretty much getting those only, can a study be designed to have a control group with similar social makeup?
 

vincent

Grumpy Old Man
Staff member
Moderator - World Affairs
Your body has dead strands of proteins all the time from dead cells. Your kidneys filter them out all the time.
Dead strands produced by your body, based on your DNA, with millions of years evolution to prevent errors, not some foreign mRNA produced in a factory process with unknown QA capability
 

Tyler

Captain
Registered Member
Dead strands produced by your body, based on your DNA, with millions of years evolution to prevent errors, not some foreign mRNA produced in a factory process with unknown QA capability
Which vaccines are you gong to take? Which is the safest and most effective?
 
Top