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sunnymaxi

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Stars and fish brains: how Chinese researchers are getting closer to mind-controlled computers​


  • Astronomy-inspired technology processes neural signals in zebrafish that could be used to control external devices
  • System may lead researchers to develop more efficient optical brain-controlled interfaces such as virtual reality
Scientists in China have harnessed the observation techniques of astronomers to scrutinise another object of mystery much closer to home – fish brains.

For the first time, researchers have scanned the neural pathways of zebrafish, a freshwater fish from the minnow family, to produce an imaging analysis of up to a hundred thousand neurons.

The real-time imagery of the neurons is a significant advance in
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, an emerging field in which machines and devices can be controlled with thoughts.

“It generates feedback signals by continuously monitoring the activities of the zebrafish brain’s entire network of neurons with a feedback delay of less than 70.5 milliseconds, and it can handle data streams up to 500 megabytes per second,” a statement on the Chinese Academy of Sciences (CAS) website said on Wednesday.

“This advancement may lead researchers to develop more efficient optical brain-computer interface technologies in the future,” the statement said, adding that the research method qualified for a patent called “Optical Brain-Computer Interface System and Methods”.

The study was published in Nature Neuroscience on March 11 by brain scientists Mu Yu and Du Jiulin, from the Centre for Excellence in Brain Science and Intelligence Technology at CAS, and algorithm specialist Hao Jie, from the Institute of Automation at CAS.
The human brain is made up of hundreds of different types of neurons – nearly 100 billion in total – while the universe comprises about 200 billion known galaxies, interconnected in a network similar to the structure of the brain. The structural resemblance has prompted theoretical speculation that the universe is much like a vast human brain.

Scientists know that human perception, learning, memory and emotions involve the collaboration of multiple regions of the brain. Extracting information from neurons is akin to finding patterns in the vast expanse of the galaxy. But the ability to process such huge amounts of data remains a significant challenge.

Astronomers have faced similar challenges in the study of
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(FRBs) – deep-space blasts of energy that are the subject of intense interest. FRBs have extremely short durations – often only a fraction of a second – and rarely repeat.

However, scientists have been able to speed up the research by pinpointing FRBs in vast amounts of astronomical data with the help of computer learning powered by graphics processing units.

Inspired by this technology, the Chinese researchers created a way to process neural signals in zebrafish. The system collects signals from optical sensors and sends them to a computer system in real-time. The system is fast – able to analyse complex signals, decode them and produce responses that allow the brain to act like a light-controlled switch that could theoretically control external devices.

“The system has been tested in three neuroscience research scenarios, including real-time optogenetic stimulation, real-time visual stimulation, and
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control,” the report said.
Using this system, the researchers said they aim to identify characteristics of neural activity that could be suitable for optical BCI and reveal their mechanisms, which would eventually lead to more efficient optical BCI technologies.

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tphuang

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apple completely missing out on the entire Chinese supply chain with their move to bow down to US political pressure to decouple from China. New iphones are not making any progress except using the latest TSMC process. Other factors like AI, satcom, camera quality and charging speed. They are falling way behind.

 

tacoburger

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In a milestone for the transplantation of animal organs into people, a 50-year-old clinically dead man in China has become the first person to receive a liver from a pig. With consent from the man’s family, researchers stitched the organ, from a genetically engineered miniature pig, to the man’s blood vessels, where it remained for ten days. It has been surgically removed today, says Dou Kefeng, one of the surgeons who led the transplant at Xijing Hospital of the Air Force Medical University in Xi’an. “Our study has just been terminated, and the colour and texture of the pig liver [transplant] are generally normal.”

The procedure was intended to test whether genetically modified pig organs could one day be used to supply hospitals for transplants. In China alone, hundreds of thousands of people experience liver failure every year, but only around 6,000 received a liver transplant in 2022. In the past few years, surgeons in the United States have transplanted pig hearts into two living people, and transplanted hearts and kidneys to several people declared dead because they lack brain function.

The Xijing surgeons say the pig liver secreted more than 30 millilitres of bile every day, a sign that it was functioning.

Researchers who specialize in transplanting animal organs into people, known as xenotransplantation, are eager to see more details about the procedure’s safety and functional benefits, and to learn from the work.

“This is a really exciting study,” says Ping Li, a transplant researcher at Indiana University School of Medicine in Indianapolis.
On 10 March, the Xijing Hospital team, including Dou, Tao Kaishan and Wang Lin transplanted a pig liver weighing 700 grams into the donor, who lacked cognitive function. The surgery took roughly nine hours to perform. The donor received a daily regimen of immunosuppressive drugs, and his original liver was left in place.

The liver came from a Bama miniature pig (Sus scrofa domestica) bred by the company Clonorgan Biotechnology in Chengdu, China. It contained six genetic modifications, says Wang. These deactivated three genes for proteins found on the surface of pig cells and introduced three genes for human proteins, to prevent the donor from rejecting the pig organ. The researchers plan to repeat the procedure in another clinically dead person later this year — and next time they will remove the person’s existing liver.
 

tacoburger

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If I recall correctly, in the US where they tried pig organ transplants, after a few weeks/months of getting the transplant, the patient died
There's a reason why they transplanted it into a brain dead patient for this attempt. Honestly that's a great way of doing medical research. I have known families that have kept clinically brain dead patient with no chance of recovery alive for years, costing lots and lots of work and resources for hospitals.
 
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