Coronavirus 2019-2020 thread (no unsubstantiated rumours!)


Breadbox

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Those isolation facilities are now known to have been key in China's ability to stop the virus. However, the early reports of these quarantine centres were widely derided by the media as draconian and some sort of communist crime against humanity.
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Even if the media did not present the story this way, most people already conditioned in their mind to think so. You could always count oh comments like "When do they gas them?", "Chinazi concentration camp", "DEMOCRACY RULEZZ, COMMIES DROOL", etc.
To say that I sympathise with the United States at this stage would be a huge lie, the suffering of others has never been more than spectacles and outlet for phoney sanctimony for them, the demand for those are huge and the MSM supply what is demanded.
 

vesicles

Colonel
I'm not a virologist, but know a little bit about genetics.

Firstly, let me define a few terms.

RaTG13 is the name of the known coronavirus found on a bat species thought to be the original host of SARS-CoV2 (not sure how certain it is though).

Genome assembly is a way to determine the DNA sequence of something. It basically uses computational methods to assemble sequences of short stretches of DNA fragments and eventually get the sequence of the entire organism.

Amplicons are either the sources or products of natural or artificial gene amplification and duplication. Amplicons can be artificially generated through many lab gene amplification methods... Hehehe... I can almost smell the blood of many conspiracy theorists is boiling at this moment :p:);) Well, amplicons also form naturally through gene duplication in several types of cancer, where certain sections of the chromosome is amplified and moved to somewhere else, which leads to cancer.

In the context of viruses, you generate amplicons whenever you want to detect or study a DNA sample. For instance, a patient comes to you and asks you to test him for COVID-19. You take his sputum and pop it into a polymerase chain reaction (PCR) machine. Most of the currently available test kits for COVID-19 use PCR to amplify viral DNA so that we can identify the viral particles. The process of PCR extensively amplifies the viral DNA and generates a whole series of amplicons, which we can use to compare with a library of viral amplicons on file to identify the virus. If his sample contains a positive match, he has COVID-19. In that sense, we use PCR to intentionally generate a whole bunch of amplicons, like how we use magnifying glass to magnify certain parts of a painting to help us judge whether the painting belongs to a famous painter.

OK, in the tweet, Alina Chan is wondering if Shing Hei Zhan will try to analyze the sequence of the known bat coronavirus again. I don't know what amplicons reads of 2018 are. It must be another the sequence of another coronavirus that someone analyzed back in 2018. And she wants to compare the original bat coronavirus with the 2018 coronavirus, I guess.
 

vesicles

Colonel
Vaccines are for prevention of infection. we also need drugs to cure the infected too.
Unfortunately, drugs are even harder to come by. We've been dealing with influenza for many decades. Many many effective vaccines have been developed and widely used by the entire world, while no effective drug has been developed. I honestly don't think we will have any drugs for COVID-19 in any foreseeable future...
 

Red Moon

Junior Member
I'm not a virologist, but know a little bit about genetics.

Firstly, let me define a few terms.

RaTG13 is the name of the known coronavirus found on a bat species thought to be the original host of SARS-CoV2 (not sure how certain it is though).

Genome assembly is a way to determine the DNA sequence of something. It basically uses computational methods to assemble sequences of short stretches of DNA fragments and eventually get the sequence of the entire organism.

Amplicons are either the sources or products of natural or artificial gene amplification and duplication. Amplicons can be artificially generated through many lab gene amplification methods... Hehehe... I can almost smell the blood of many conspiracy theorists is boiling at this moment :p:);) Well, amplicons also form naturally through gene duplication in several types of cancer, where certain sections of the chromosome is amplified and moved to somewhere else, which leads to cancer.

In the context of viruses, you generate amplicons whenever you want to detect or study a DNA sample. For instance, a patient comes to you and asks you to test him for COVID-19. You take his sputum and pop it into a polymerase chain reaction (PCR) machine. Most of the currently available test kits for COVID-19 use PCR to amplify viral DNA so that we can identify the viral particles. The process of PCR extensively amplifies the viral DNA and generates a whole series of amplicons, which we can use to compare with a library of viral amplicons on file to identify the virus. If his sample contains a positive match, he has COVID-19. In that sense, we use PCR to intentionally generate a whole bunch of amplicons, like how we use magnifying glass to magnify certain parts of a painting to help us judge whether the painting belongs to a famous painter.

OK, in the tweet, Alina Chan is wondering if Shing Hei Zhan will try to analyze the sequence of the known bat coronavirus again. I don't know what amplicons reads of 2018 are. It must be another the sequence of another coronavirus that someone analyzed back in 2018. And she wants to compare the original bat coronavirus with the 2018 coronavirus, I guess.
Thank you for your explanations of everything. I think you guessed correctly about conspiracy theorists, and I think the inquirer was indeed searching for conspiracy theories when he stumbled on this tweet.
 

AssassinsMace

Brigadier
I'm watching on TV the latest Republican in Congress who's an ally of Trump's coronavirus response and refuses to where a mask and was just diagnosed with COVID-19 claim that the few times he did wear a mask was why he got COVID-19. His logic was he was breathing with the mask on meaning he infected himself because his air he was exhaling was trapped in the mask...
 

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