While China doesn't start out with good ground based air defence over Taiwan due to local resistence, they still have full complements of air patrols that will be devoted to stopping American attacks, as well as naval based AAMs.Why is the defense minister saying this? Shouldn't their Head of state or Foreign affairs department strongly condemn such plans or alternatively beg and grovel for their overlord not to do it? This is a political problem, not a military one, as Taiwan has zero military means of stopping it from happening.
I shall quote Henry Kissinger again: "To be an enemy of the US is dangerous, but to be a friend is fatal."
So I think American being able to bomb Taiwan province is questionable. A few attacks might hit, but as shown by the Ukraine war, you need long term sustained bombing to have a major effect. Just the presence of CAP and naval air defense will restrict attacks to long range missiles only, which are more easily interceptable. Admittedly the island is not anywhere near as defended as other areas, but as Beijing rolls back the KMT forces, that will change.